I missed this last year! The answer to one of my long-lasting questions: is psoriasis a chronic inflammatory disease or an autoimmune disease? For until today I thought it was a chronic inflammatory disease because, as yet, no autoantigen had been identified. Of course, this was puzzling as then it was difficult to understand what […]
Dear All, I am extremely pleased to invite you to contribute to a special issue on “Innate T Cell Development and Functions in Immune Diseases” which will be published in Journal of Immunology Research in March 2016. You can find the Call for Papers for this Special Issue at http://www.hindawi.com/journals/jir/si/641274/cfp/ and the deadline for submission […]
A major event on Immunology is about to happen in Portugal! What?? you must be thinking… The Annual Meeting of the society of immunology of course! The meeting will celebrate its 40th Birthday, not bad hey ! And it will take place at the Instituto de Medicina Molecular in Lisboa :] On the SPI website […]
The laboratory of Joonsoo Kang provides us with a very nice example of how to follow up a resource paper published in Nature Immunology Narayan et al 2012 that had performed a genome wide gene expression analysis specifically associated with Vγ chain restriction. This month they describe the minimal core transcriptional requirement, which is formed […]
The choice of the second paper that I will present in 2013 is equally as important as the first one, and funnily once again it is a paper that follows one of the best presentations at ECI in Glasgow (see meeting report here – 06/10/2012). The very challenging talk from Jessica Strid is indeed now […]
Auto-promo! Did I tell you that I have been invited to give a talk at the 16th Colloque Cytokines et Chimiokines du Croisic? Here you will find the excellent Program of the meeting :] and here is the poster!
The choice of the first paper presented in 2013 is important! So here it is :] The fantastic talk that Shimon Sakaguchi gave, on regulatory T cells of course, at ECI in Glasgow (see meeting report here – 06/10/2012), is now available to everyone as publication in Immunity! This paper goes very well with my […]
We are at a very special time, and probably turning point, in our understanding of the sequences of events that govern the differentiation of naïve CD4 T cells into T helper functional subsets. There have been three major papers published this year in Cell and that will change our view on the role and function […]
A last minute to say that I will go to the XXXVIII Annual Meeting of the Portuguese Society of Immunology (SPI) in Porto to present a poster with some data on «Transcriptional and epigenetic signatures of pro-inflammatory γδ T cell subsets». Thus, if you want to have a look here is the link: XXXVIII Annual […]
Here is, published :], the story that Marie-Laure Michel, from Hayday’s lab, presented at the 5th γδ T cell conference in Freiburg earlier this year. She demonstrates the importance of IL-7 in expanding IL-17-producing CD27- γδ T cells in vitro and in vivo. Administration of recombinant IL-7 three times over 5 days leads to an […]